Sciteck’s Solution to the antiquated method of DIPSTICK urinalysis is a paradigm shift in how we think about the diagnostic value of urine

   The AutoUA® System by Sciteck is a user-friendly, automated analyzing system for the quantitative and semi-quantitative analysis of fifteen (15) analytes in human urine that can provide up to 29 results. The system includes tests for pH, specific gravity, ketone bodies, beta-hydroxybutyric acid, bile acids ¹, blood (Hgb), leukocyte esterase (WBC), nitrite, micro-protein (total), glucose, bilirubin, urobilinogen, creatinine and electrolytes (Na, K and Cl). The Sciteck AutoUA® core system of reagents is FDA Cleared.

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Sciteck's AutoUA® Informational Video  

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   The AutoUA® FDA cleared urinalysis reagent system is compatible with the Global, Olympus series, Beckman and open channel analyzers. Currently, the Sciteck system of reagents is used by small and large reference laboratories as well as small hospital laboratories providing an alternative to the use of dipstick or dipstick technology. The use of our system allows a laboratory to preform urinalysis on a truly "walk-away" basis. This reagent system can be used in the small single physician POL or in a large reference lab. For example, a single Olympus 5800 operated by one technician can run approximately 6000 tests tests per hour. The fastest strip readers for example can run about 120 samples per hour. The cost of running thousands of specimens per hour on 8 or 10 automated strip readers requiring 6 to 8 technicians cannot be compared to the more efficient use of the Olympus 5800 and one technician. In the small POL a FDA cleared Global 240 can run 24 AutoUA® panels on a walk away basis providing the Physician with up to 29 urine values providing quantitative, qualitative, normalized and clinically significant urine values that are designed to give the Clinician more meaningful values to aid in better treatment at the point of care. 

   Not only does the AutoUA® system provide a savings between the reagents cost compared to the cost of dipsticks, but also a much larger savings in time and personnel. 


AutoUA® - Quick Resources 

AutoUA® vs AMES Dipsticks

AutoUA® Calibrators & Controls

 AutoUA® Insert


AutoUA® - Veterinary

AutoUA® Vet - Automated Urinalysis System Insert


The Power of AutoUA® Automated Urinalysis Reagent Systems


   Sciteck and the companies it evolved from (Chimera Research) began providing liquid reagents to laboratories for urinalysis on automated chemistry analyzers in 1989. Some of the advantages of using the liquid reagents to obtain quantitative results include such things as:

1) Utilization of equipment already on hand. For instance, many laboratories have one or more clinical chemistry analyzers with open channel capability that are underutilized (e.g. Hitachi, Beckman, Olympus, and Mira instruments) which are compatible with these reagents. Thus, it may not be necessary to purchase equipment.

2) Results for each analyte may be reported in true, quantitative units instead of current vague subjective terms (i.e. trace, moderate and large).

3) Because these assays utilize automated chemistry analyzers to produce quantitative results, a traditional and effective quality control program can be used from the software that is on-board the analyzers. 

4) Use of a single automated chemistry analyzer for quantitative urinalysis and standard, quantitative serum chemistries can provide new, improved data for the attending physician. This is achieved by combining the quantitative data for urine and serum obtained using formulas and indices to produce valuable clinically significant information.



An Overview of AutoUA® and it's Benefits



   Historically, the first urinalysis was actually the beginning of laboratory medicine. References to the study of urine can be found in the pre-civilized drawings of cavemen and also in the Egyptian hieroglyphics such as the Edwin Smith Surgical Papyrus. The early physicians depicted in these ancient drawings often never saw the patient, only the patient’s urine. Although these physicians lacked the sophisticated testing mechanisms now available, they were able to obtain basic diagnostic information ². The evolution of urinalysis continues from ancient times to the dry chemistry methods (dipsticks) of yesterday to the automated liquid urinalysis system of today that is capable of providing clinically significant values while saving time and money.


   The AutoUA® system of reagents is compatible with the Hitachi 717, 911, 747, the Olympus series, Beckman, and other auto-analyzers. Currently, the Sciteck system of reagents is used by large reference laboratories as well as small hospital laboratories providing an alternative to the use of dipstick or dipstick technology. The use of our system allows a laboratory to perform a urinalysis on a truly “walk-away” basis. For example, a single Hitachi 747-200 operated by one technician can run approximately 4800 tests per hour. The fastest strip readers, for example, can run no more than about 600 urine tests per hour.

   The cost of running thousands of specimens per hour on 8 or 10 automated strip readers requiring 6 to 8 technicians cannot be compared to the more efficient use of one Hitachi 747-200 and one technician. Not only does the AutoUA® system provide savings between the reagents costs compared to the cost of dipsticks, but also a much larger savings in time and personnel.


1. Selectivity: Profile and panels for urinalysis can be selected and run in accordance with client preference thereby providing cost savings to the laboratory and to the customer as well.

2. Clinically significant indices can be calculated from the data:

RFI (renal failure index), this is an expression of the urinary sodium concentration as a function of urine creatinine to serum creatinine.

FE (Fractional Excretion of Sodium), this is an expression of the fraction of filtered sodium that escapes reabsorption and is excreted into the urine. Early warning of volume depletion for hospitalized patients on I.V. is often difficult to detect at the bedside. Detection could easily prevent acute renal failure and subsequent transfer to ICU.

NI (Nutritional Index) is determined by serum BUN indexed to urine creatinine.

P/C Ratio (Protein / Creatinine ratio) is an expression of protein concentration relative to creatinine in un-timed specimens is another way to avoid the necessity of collection of a 24-hour urine. Urinary protein/creatinine concentration ratios in excess of 3.5 usually indicate nephrotic range protein urea.

BHA:AcAa (Beta-Hydroxybutyric acid : Acetoacetic acid ratio): Urinalysis dipsticks only measure acetoacetic acid  (AcAa) in urine which is 20% of the total ketone bodies excreted in urine. Sciteck's AutoUA® allows the detection of the major portion of the ketone body excreted in urine which is BHA that accounts for 78% of the total ketone excreted in urine. At the on set of ketosis the BHA will be detectable first and the ratio of BHA:AcAa in monitoring for ketoacidosis is very important.

3. Normalizing: The Sciteck AutoUA® also allows for the normalizing of urine for its correct concentration which will improve the accuracy and precision of the urine test result. A concentrated urine may yield a 3+++ glucose on a dipstick but when it is normalized it is only a trace amount. In the reverse, a dilute urine with a trace amount of protein is a 3+++ after normalization. 

4. Low urine volume requirements of less than 200uL of urine for a full 29 result panel. This can be very important with pediatric, elderly and other patient populations where the obtainment of large amounts of urine is not possible.

4. Sciteck will provide the Global 240 or 4500 FDA cleared analyzer that can meet all the needs of your laboratory. The Globals can be provided to you based on reagent purchase volumes and length of contract. The reagent system utilizes 11 to 15 slots on the auto-analyzer leaving 20 empty reagent slots available for expansion of the AutoUA® system and your use for esoteric testing, chemistry, drug screening, etc. In addition, at the end of the contract the instrument belongs to you.

These are only a few of the examples of why the AutoUA® system is the next step in the evolution of urinalysis!




The AutoUA® is compatible with any open channel analyzer.  


For Additional information about the AutoUA® series or our Custom Calibrators, Controls and Reagents please contact us at info@sciteck.org


1. This assay is still currently in development.
2. S.K. Strasinger, Urinalysis and Body Fluids. F.A. Davis Co., Phil 1994.
3. Kaplan, R.E., Springate, J.E., and Feld, L.G. Screening Dipstick Urinalysis: A Time to Change. Pediatrics. 1997; 100:919-921.

Ordering information:
Phone: 828-650-0407 / 800-749-4537
Fax: 828-650-2735
e-mail: info@sciteck.org