Diagnostics

 

Sciteck’s Solution to the antiquated method of DIPSTICK urinalysis is a paradigm shift in how we think about the diagnostic value of urine

The Auto UA System by Sciteck is a user-friendly, automated analyzing system for the quantitative and semi-quantitative analysis of fifteen (15) analytes in human urine. The system includes tests for pH, specific gravity, ketone bodies, beta-hydroxybutyric acid, bile acids ¹, blood (Hgb), leukocyte esterase (WBC), nitrite, micro-protein (total), glucose, bilirubin, urobilinogen, creatinine and electrolytes (Na, K and Cl).

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                                          Sciteck's Auto-UA® Informational Video  



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The AUTO-UA® system of reagents is compatible with the Hitachi 717, 911, 747, the Olympus series, Beckman, and other auto-analyzers. Currently, the Sciteck system of reagents is used by large reference laboratories as well as small hospital laboratories providing an alternative to the use of dipstick or dipstick technology. The use of our system allows a laboratory to preform urinalysis on a truly "walk-away" basis. For example, a single Hitachi 747-200 operated by one technician can run approximately 4800 tests tests per hour. The fastest strip readers for example can run as many as 5,000 assays per hour. The cost of running thousands of specimens per hour on 8 or 10 automated strip readers requiring 6 to 8 technicians cannot be compared to the more efficient use of the Hitachi 747-200 and one technician. Not only does the AUTO-UA® system provide a savings between the reagents cost compared to the cost of dipsticks, but also a much larger savings in time and personnel. 

 

Auto-UA® - Quick Resources 

AUTO-UA® BROCHURE

AUTO-UA® vs AMES Dipsticks

AUTO-UA® Calibrators & Controls

AUTO-UA® INSERT

SCITECK PRODUCT CATALOG

 

 

The Power of AUTO-UA® Automated Urinalysis Reagent Systems

 

Sciteck and the companies it evolved from (Chimera Research) began providing liquid reagents to laboratories for urinalysis on automated chemistry analyzers in 1989. Some of the advantages of using the liquid reagents to obtain quantitative results include such things as:

1) Utilization of equipment already on hand. For instance, many laboratories have one or more clinical chemistry analyzers with open channel capability that are underutilized (e.g. Hitachi, Beckman, Olympus, and Mira instruments) which are compatible with these reagents. Thus, it may not be necessary to purchase equipment.

2) Results for each analyte may be reported in true, quantitative units instead of current vague subjective terms (i.e. trace, moderate and large).

3) Because these assays utilize automated chemistry analyzers to produce quantitative results, a traditional and effective quality control program can be used from the software that is on-board the analyzers. 

4) Use of a single automated chemistry analyzer for quantitative urinalysis and standard, quantitative serum chemistries can provide new, improved data for the attending physician. This is achieved by combining the quantitative data for urine and serum obtained using formulas and indices to produce valuable clinically significant information.

  

 

An Overview of Auto-UA® and it's Benefits

 

HISTORY

Historically, the first urinalysis was actually the beginning of laboratory medicine. References to the study of urine can be found in the pre-civilized drawings of cavemen and also in the Egyptian hieroglyphics such as the Edwin Smith Surgical Papyrus. The early physicians depicted in these ancient drawings often never saw the patient, only the patient’s urine. Although these physicians lacked the sophisticated testing mechanisms now available, they were able to obtain basic diagnostic information ². The evolution of urinalysis continues from ancient times to the dry chemistry methods (dipsticks) of yesterday to the automated liquid urinalysis system of today that is capable of providing clinically significant values while saving time and money.

COMPATIBILITY

The AUTO-UA® system of reagents is compatible with the Hitachi 717, 911, 747, the Olympus series, Beckman, and other auto-analyzers. Currently, the Sciteck system of reagents is used by large reference laboratories as well as small hospital laboratories providing an alternative to the use of dipstick or dipstick technology. The use of our system allows a laboratory to perform a urinalysis on a truly “walk-away” basis. For example, a single Hitachi 747-200 operated by one technician can run approximately 4800 tests per hour. The fastest strip readers, for example, can run no more than about 600 urine tests per hour.

The cost of running thousands of specimens per hour on 8 or 10 automated strip readers requiring 6 to 8 technicians cannot be compared to the more efficient use of one Hitachi 747-200 and one technician. Not only does the AUTO-UA® system provide savings between the reagents costs compared to the cost of dipsticks, but also a much larger savings in time and personnel.

ADDITIONAL BENEFITS

1. Selectivity: Profile and panels for urinalysis can be selected and run in accordance with client preference thereby providing cost savings to the laboratory and to the customer as well.

2. Clinically significant indices can be calculated from the data:

  RFI (renal failure index), this is an expression of the urinary sodium concentration as a function of urine creatinine to serum creatinine.
  FE (Fractional Excretion of Sodium), this is an expression of the fraction of filtered sodium that escapes reabsorption and is excreted into the urine. Early warning of volume depletion for hospitalized patients on I.V. is often difficult to detect at the bedside. Detection could easily prevent acute renal failure and subsequent transfer to ICU.
  NI (Nutritional Index) is determined by serum BUN indexed to urine creatinine.
  P/C Ratio (Protein / Creatinine ratio) is an expression of protein concentration relative to creatinine in un-timed specimens is another way to avoid the necessity of collection of a 24-hour urine. Urinary protein/creatinine concentration ratios in excess of 3.5 usually indicate nephrotic range protein urea.

3. Low volume requirements of less than 1.0 mL.

4. Sciteck will provide an analyzer that will meet the needs of your laboratory. Instruments are provided to you based on reagent purchase volumes and length of contract. The reagent system utilizes 11 to 13 slots on the auto-analyzer leaving approximately 17 empty reagent slots available for expansion of the AUTO-UA® system and your use for esoteric testing, chemistry, drug screening, etc. In addition, at the end of the contract the instrument belongs to you.


These are only a few of the examples of why the AUTO-UA® system is the next step in the evolution of urinalysis!

AUTO-UA® Cost Comparison Study

 


 


BUSINESS COST ANALYSIS

 

Current cost for a lab conducting 100,000 UA’s per annum via UA dipsticks:

Cost / UA

Cost = Dipsticks + Labor: (100,000 x $0.62) + (100,000 x $1.89)* = $251,000

UA = Annual Volume: 100,000

= $2.00 UA

AUTO-UA® decreases costs 144% for labs conducting 100,000 urines per annum.

 

 

Proposed costs for utilizing AUTO-UA® ( 11 ) automated urinalysis system:

Cost / UA

Cost = Annual reagent cost + Labor: ($65,000.00) + (100,000 x $0.375) = $102,500

UA = Annual Volume: 100,000

Formula assumes a 5 fold decrease in labor costs for use of Auto-analyzer

*This figure is conservative based on analysis cited in article 3 which indicates actual costs per dipstick UA to be between $2.51 and $3.24.

 

 

For Additional information about the AUTO-UA® series or our Custom Calibrators, Controls and Reagents please contact us at info@sciteck.org

 


References:
1. This assay is still currently in development.
2. S.K. Strasinger, Urinalysis and Body Fluids. F.A. Davis Co., Phil 1994.
3. Kaplan, R.E., Springate, J.E., and Feld, L.G. Screening Dipstick Urinalysis: A Time to Change. Pediatrics. 1997; 100:919-921.


Ordering information:
Phone: 828-650-0407 / 800-749-4537
Fax: 828-650-2735
e-mail: info@sciteck.org